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12 , 14 Oral contraceptive medications, a common method of birth control, are mostly metabolized by cytochrome-P450 (CYP450)

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doi: 10.3389/fcimb.2024.1484371 69 JiminezJAUwieraTCAbbottDWUwieraRREInglisGD

They work by mimicking the action of a natural hormone in the body, helping to regulate blood sugar levels and insulin production

To support tolerance, GLP-1 treatment is started at a low dose and titrated upward, which helps reduce gastrointestinal side effects like nausea that can affect 20% to 40% of patients when treatment begins , as noted in the earlier payer-focused clinical guidance